Modulating gene translational control through genome editing

Potential Application of Novel DNA Editing Techniques in Translational Neuroscience

No abstract is provided.

Antiviral Defenses in Plants through Genome Editing

Plant-virus interactions based-studies have contributed to increase our understanding on plant resistance mechanisms, providing new tools for crop improvement. In the last two decades, RNA interference, a post-transcriptional gene silencing approach, has been used to induce antiviral defenses in plants with the help of genetic engineering technologies. More recently, the new genome editing syst...

Mechanism of tRNA-dependent editing in translational quality control.

Protein synthesis requires the pairing of amino acids with tRNAs catalyzed by the aminoacyl-tRNA synthetases. The synthetases are highly specific, but errors in amino acid selection are occasionally made, opening the door to inaccurate translation of the genetic code. The fidelity of protein synthesis is maintained by the editing activities of synthetases, which remove noncognate amino acids fr...

potential application of novel dna editing techniques in translational neuroscience

no abstract is provided.

Genome Editing